Category: Science


We Are Melanoma Research: MRA 2024 Annual Report

26 November 2024 In Allies & Partnerships, Events, Melanoma Stories, News, Policy, Prevention, Science, Treatment

Driven by our audacious goal to end suffering and death due to melanoma, the Melanoma Research Alliance has been boldly leading scientific discoveries that translate into improved patient outcomes and renewed hope since 2007. Throughout our 2024 report, We Are Melanoma Research, you’ll find highlights of our most recent accomplishments, as well as stories of the researchers, clinicians, patients, and advocates who make this progress possible.

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George Mannes' Acral Melanoma Story

By Renee Orcione, MRA Digital Engagement & Communications Manager | 25 November 2024 In Melanoma Stories, Science, Treatment

George Mannes, a longtime writer and editor based in New York City, is sharing his acral melanoma journey in the hopes that more people will become aware of this lesser-known rare melanoma subtype. Acral melanoma, sometimes called acral lentiginous melanoma (ALM), forms on the palms, soles of feet, or under...

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MRA Meet Ups: Be Your Biggest Advocate - Navigating a Melanoma Diagnosis

By Renee Orcione, MRA Digital Engagement & Communications Manager | 21 November 2024 In Allies & Partnerships, Events, Melanoma Stories, Prevention, Science, Treatment

On November 20th, MRA hosted its very first online discussion in its new series MRA Meet-Ups, where we regularly connect with the melanoma community to discuss important topics, share insights and experiences, and ask questions. The session, called "Be Your Biggest Advocate: Navigating a Melanoma Diagnosis", featured a panel of...

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Commemorating Indigenous Peoples’ Day: What American Indian/Alaska Native People Should Know About Melanoma

30 October 2024 In Allies & Partnerships, Prevention, Science

Indigenous Peoples' Day, which commemorates American Indian/Alaska Native history, traditions, and culture, was celebrated across the US on October 14, 2024. In honor of these celebrations, we highlight what American Indian/Alaska Native people should know about melanoma.

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Clinical Trials to Watch: September 2024

By Joan Levy, PhD - MRA Chief Science Officer | 26 September 2024 In Allies & Partnerships, News, Science, Treatment

Treatment of advanced melanoma has dramatically improved over the past decade with 17 new therapies approved by the Food and Drug Administration (FDA). Even with these treatment advances, 50% of patients with advanced melanoma will either not respond to any of these treatments or their disease will progress, creating a...

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IGNYTE-3 Trial: Harnessing the Power of Viruses to Activate the Immune System and Treat Advanced Melanoma

23 September 2024 In Allies & Partnerships, Events, News, Science, Treatment

Although treatment options for advanced melanoma have improved, many patients still will not benefit from currently approved therapies. In particular, some patients treated with anti-PD1 immunotherapy never respond (called primary resistance) and others initially respond and then their disease progresses (called secondary resistance).

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2025 Scientific Retreat & Patient Forum Scholarship

9 September 2024 In Allies & Partnerships, Events, Melanoma Stories, Prevention, Science, Treatment

MRA’s Patient Advocate Scientific Retreat & Patient Forum Scholarship encourages the engagement, education, and inclusion of patient advocates in melanoma research by providing support for their attendance at the Annual Melanoma Exchange Patient Forum and Scientific Retreat.

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Investigating CAR-T Cell Therapy for Advanced Melanoma

By Renee Orcione, MRA Digital Engagement & Communications Manager | 28 August 2024 In Allies & Partnerships, News, Science, Treatment

One of the greatest scientific breakthroughs in melanoma research has been the FDA approval of cancer immunotherapy treatments called checkpoint inhibitors. These treatments stimulate the body’s own immune system to fight off melanoma. Checkpoint immunotherapies, first approved in melanoma, are now being used to treat a number of different cancer types.

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RARE Registry: Providing Hope Through Innovation

26 July 2024 In Allies & Partnerships, Events, Melanoma Stories, News, Prevention, Science, Treatment

Each year approximately 5,000 patients are diagnosed with acral or mucosal melanoma. These rare melanoma subtypes arise in non-sun exposed areas and are not believed to be caused by UV damage. Due to the relative obscurity of these rare subtypes, patients face mounting challenges ranging from late diagnoses, lack of support,...

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MRA's Latest Research Report: We Are Melanoma Research

19 July 2024 In Allies & Partnerships, Events, Melanoma Stories, News, Prevention, Science, Treatment

Each year, the Melanoma Research Alliance brings together melanoma thought leaders from across the global research community to exchange ideas, share recent scientific successes and hurdles, forge new collaborations, and connect with the patient advocate community.

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