Category: Science


Registration Now Open for March 9 Patient Forum!

11 January 2022 In Allies & Partnerships, Events, News, Policy, Prevention, Science, Treatment

MRA’s Melanoma Exchange Patient Forum, held in-person in Washington DC and virtually on March 9, will bring together melanoma patients, survivors, advocates, and their loved ones to provide lay-friendly, state-of-the-science education, promote collaboration, and provide networking opportunities across the melanoma community.

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Early Studies Suggest New Immune Checkpoint Target for Melanoma

By Cody Barnett, MPH, MRA Senior Director of Communications & Patient Engagement | 6 January 2022 In Science

Checkpoint immunotherapies have revolutionized the way melanoma is treated. However, up to 50% of patients don’t respond or go on to develop resistance to even our latest approved therapies. Thankfully, researchers such as MRA-funded investigator Roberto Tinoco, PhD are hard at work discovering the next checkpoint inhibitors capable of revving up the immune system and fighting melanoma.

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Championing Clinical Trials

By Cody Barnett, MPH, MRA Senior Director of Communications & Patient Engagement | 2 January 2022 In Melanoma Stories, Science, Treatment

Too often, the first time someone is exposed to clinical trials is when they've been diagnosed with a serious, life threatening illness. Learn how Mary Elizabeth partnered with her doctor Jedd Wolchok to take back control from melanoma.

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Advancing Rare Melanoma Research

27 December 2021 In Science

Despite the tremendous progress made in the last decade in treating melanoma, approximately one third of patients don’t benefit from currently approved therapies. This includes the majority of people with rare forms of melanoma. But as investigators continue to chip away at understanding what causes these melanomas and how they differ from UV-driven cutaneous melanomas, the hope is the better understanding they reap will be sown into improved treatments for these patients.

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MRA Applauds Expanded Approval of Pembrolizumab to Patients with Stage 2 Melanoma

By Cody Barnett, MPH, MRA Senior Director of Communications & Patient Engagement | 6 December 2021 In News, Science, Treatment

The Melanoma Research Alliance (MRA), the largest non-profit funder of melanoma research worldwide, welcomes the U.S. Food and Drug Administration (FDA) decision to expand eligibility of Merck’s Keytruda (pembrolizumab) to include patients with Stage IIB and IIC melanoma.

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Promising Uveal Melanoma Research Advances

By Cody Barnett, MPH, MRA Senior Director of Communications & Patient Engagement | 26 October 2021 In News, Science, Treatment

Uveal melanoma, often called ocular melanoma or just eye melanoma, is a rare melanoma subtype that affects about 2,500 people each year in the United States. As is true with other rare subtypes, we know far less about what causes uveal melanoma, how it progresses, and how it can be...

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Paving a Path for Cancer Vaccines

22 October 2021 In News, Science

Although vaccines to prevent COVID-19 have dominated conversations and the news cycle since the start of the pandemic — Dr. Nina Bhardwaj and her team have been busy at work with a different type of vaccine altogether: one to support melanoma treatment and reduce risk of recurrence.

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Challenge Accepted: MRA 2020 - 2021 Annual Report

19 October 2021 In Allies & Partnerships, Melanoma Stories, News, Policy, Prevention, Science, Treatment

This was a year like no other. COVID-19 presented new challenges that required new ways of thinking. At MRA, confronting challenges is part of our DNA. We never stop challenging ourselves, no matter the odds or obstacles, in pursuit of conquering melanoma and saving lives.

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Antibiotics & Treatment-Resistant Melanoma: A Stressful Subject

By Cody Barnett, MPH, MRA Senior Director of Communications & Patient Engagement | 23 September 2021 In Science

Eleonora Leucci, PhD, an MRA-funded investigator at KU Leuven (Belgium) has determined that some antibiotics may be able to slow, or even reverse, treatment resistance that melanoma develops to targeted therapies. If her preliminary findings are verified in the clinic, this would be a potent weapon in the melanoma treatment arsenal and a huge win for patients.

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The Next Frontier of Combination Immunotherapy: Maximizing the Benefits & Reducing Harms

15 September 2021 In Science, Treatment

Every general knows that the best way to successfully win a war is to deploy multiple weapons with different targets. This strategy was first used in cancer to conquer childhood leukemias with combination chemotherapy and now is being put to the test in melanoma by combining multiple checkpoint inhibitors, as...

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