Category: Treatment


What Melanoma Patients Need to Know about Hepzato Kit

By Cody Barnett, MPH, MRA Senior Director of Communications & Patient Engagement | 23 October 2023 In News, Science, Treatment

You may have heard of Hepzato Kit, also known as Liver-Directed Melphalan, the first liver-directed therapy available for patients with metastatic uveal melanoma who have liver metastases that cannot be surgically removed.

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Adjuvant Therapy: Is More Better or is Less More?

19 October 2023 In Allies & Partnerships, Events, Science, Treatment

In 2021 and 2023, the FDA expanded approval of Keytruda and Opdivo, respectively, in the adjuvant setting to include more patients with melanoma — expanding therapeutic options for a greater number of patients. These decision have created tectonic shifts in the field—opening a range of not only treatment options but also discussion points to which the medical, research, and advocacy community are split.

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Advancing Research after a Rare Diagnosis: Janet Yannelli's Acral Melanoma Journey

By Renee Orcione, MRA Digital Engagement & Communications Manager | 16 October 2023 In Allies & Partnerships, Melanoma Stories, Science, Treatment

“I had never heard of acral melanoma, even though I’m a nurse,” remarked Janet Yannelli, lifelong Maine resident. Acral melanoma is a rare melanoma subtype that accounts for about 1-3% of cases each year. Acral melanoma forms on the palms, soles of feet, or under nails.

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MRA Statement on Expanded Approval of Nivolumab to Patients with Stage 2 Disease

13 October 2023 In News, Science, Treatment

The Melanoma Research Alliance (MRA), the largest non-profit funder of melanoma research worldwide, welcomes the U.S. Food and Drug Administration (FDA) decision to expand eligibility of Bristol Myers Squibb’s Opdivo (nivolumab) to include patients with completely resected Stage IIB and IIC melanoma.

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Thriving after Advanced Melanoma at 26: John Elson’s Story

By Renee Orcione, MRA Digital Engagement & Communications Manager | 20 September 2023 In Allies & Partnerships, Melanoma Stories, Treatment

John Elson woke up – on his birthday – and discovered a lump in his neck. The New Yorker wasn’t entirely concerned and initially explained it away as a muscle knot. However, when the lump didn’t go away and he noticed a second one near his armpit, alarm bells started...

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Dr. Hussein Tawbi: Opdualag Clinical Trial Updates

By Tanisha Jackson, PhD - MRA Scientific Program Director | 18 September 2023 In Allies & Partnerships, Events, News, Science, Treatment

In March of 2022, the melanoma community celebrated the FDA approval of nivolumab + relatlimab (brand name Opdualag), a new treatment for patients with metastatic melanoma that combines two different immunotherapies, nivolumab and relatlimab, into one medicine.

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Combating Melanoma Brain Metastases and Leptomeningeal Disease

8 September 2023 In Allies & Partnerships, Events, Policy, Science, Treatment

Melanoma is the third most common source of brain metastases, exceeded only by lung and breast cancer. In addition, metastatic melanoma cells have the highest propensity for settling in the brain out of any solid tumor.

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MRA Statement on FDA Approval of Hepzato Kit for Patients with Uveal Melanoma with Liver Metastases

16 August 2023 In News, Treatment

The Melanoma Research Alliance (MRA) released the following statements from MRA Chief Science Officer Joan Levy, PhD and MRA Chief Executive Officer Marc Hurlbert, PhD on the Food & Drug Administration approval of Hepzato Kit for patients with uveal melanoma with liver metastases that cannot be surgically removed.

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MRA's Latest Research Report: Reaching for the Stars

25 July 2023 In Allies & Partnerships, Events, Melanoma Stories, News, Policy, Prevention, Science, Treatment

Each year, MRA convenes global thought leaders from across the melanoma research community to exchange ideas, report on scientific successes and challenges, and network and forge new collaborations.

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Reflecting on a Decade of Progress and Future Heights in Melanoma

21 July 2023 In Allies & Partnerships, News, Science, Treatment

If you told Dr. Jedd Wolchok at the start of his oncology career what melanoma research would look like today, he likely wouldn’t believe you. Wolchok, now a world-renowned medical oncologist and Meyer Director of the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine, originally faced an alternate...

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